منابع مشابه
Prenatal Screening Using Maternal Markers
Maternal markers are widely used to screen for fetal neural tube defects (NTDs), chromosomal abnormalities and cardiac defects. Some are beginning to broaden prenatal screening to include pregnancy complications such as pre-eclampsia. The methods initially developed for NTDs using a single marker have since been built upon to develop high performance multi-maker tests for chromosomal abnormalit...
متن کاملCorrection: Prenatal Ultrasound Screening: False Positive Soft Markers May Alter Maternal Representations and Mother-Infant Interaction
BACKGROUND In up to 5% of pregnancies, ultrasound screening detects a "soft marker" (SM) that places the foetus at risk for a severe abnormality. In most cases, prenatal diagnostic work-up rules out a severe defect. We aimed to study the effects of false positive SM on maternal emotional status, maternal representations of the infant, and mother-infant interaction. METHODOLOGY AND PRINCIPAL F...
متن کاملPrenatal genetic screening for Down syndrome and open neural tube defects using maternal serum markers in Thai pregnant women.
Maternal serum screening has gained widespread acceptance as a major prenatal screening tool for chromosomal abnormalities in the US and Europe since Merkatz et al described an association between low maternal serum alpha fetoprotein (AFP) levels and increased risk for trisomy 21 in 1984. In 1988, Wald et al proposed a screening program based on maternal age in combination with three biochemica...
متن کاملPrenatal maternal plasma DNA screening for cystic fibrosis: A
Prenatal cystic fibrosis (CF) screening is currently based on Background: determining the carrier status of both parents. We propose a new method based only on the analysis of DNA in maternal plasma. The method relies on the quantitative amplification of the CF gene to Methods: determine the percentage of DNA fragments in maternal plasma at targeted CF mutation sites that carry a CF mutation. C...
متن کاملPrenatal fetal karyotyping and maternal serum alpha-fetoprotein screening.
Prenatal karyotyping was undertaken in 569 consecutive amniotic fluid samples where the indication for amniocentesis was two sequential raised maternal serum alpha-fetoprotein concentrations. In 475 successful cultures five chromosome abnormalities were found--four constitutional anomalies (47,XXY; 47,XYY; an inherited inv(8) (p23q11); and a de-novo translocation t(6;7) (p11;p22) and a culture-...
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ژورنال
عنوان ژورنال: Journal of Clinical Medicine
سال: 2014
ISSN: 2077-0383
DOI: 10.3390/jcm3020504